A carregar...

Histone Deacetylase Inhibitors through Click Chemistry

Histone deacetylase inhibitors (HDACi) are a relatively new class of chemotherapy agents. Herein, we report a click-chemistry based approach to the synthesis of HDACi. Fourteen agents were synthesized from the combination of two alkyne and seven azido precursors. The inhibition of HDAC1 and HDAC8 wa...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Shen, Jie, Woodward, Robert, Kedenburg, James Patrick, Liu, Xianwei, Chen, Min, Fang, Lanyan, Sun, Duxin, Wang, Peng George
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441833/
https://ncbi.nlm.nih.gov/pubmed/19007204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm8005355
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!