LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors

Mutations in the LRRK2 gene are the most common cause of genetic Parkinson’s disease. Although the mechanisms behind the pathogenic effects of LRRK2 mutations are still not clear, data emerging from in vitro and in vivo models suggests roles in regulating neuronal polarity, neurotransmission, membra...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Hinkle, Kelly M, Yue, Mei, Behrouz, Bahareh, Dächsel, Justus C, Lincoln, Sarah J, Bowles, Erin E, Beevers, Joel E, Dugger, Brittany, Winner, Beate, Prots, Iryna, Kent, Caroline B, Nishioka, Kenya, Lin, Wen-Lang, Dickson, Dennis W, Janus, Christopher J, Farrer, Matthew J, Melrose, Heather L
التنسيق: Artigo
اللغة:Inglês
منشور في: BioMed Central 2012
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441373/
https://ncbi.nlm.nih.gov/pubmed/22647713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-7-25
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