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Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice

The generation and maturation of adult neural stem/progenitor cells are impaired in many neurodegenerative diseases, among them Parkinson’s disease (PD). In mammals, including humans, adult neurogenesis is a lifelong feature of cellular brain plasticity in the hippocampal dentate gyrus (DG) and in t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Winner, B, Melrose, HL, Zhao, C, Hinkle, KM, Yue, M, Kent, C, Braithwaite, AT, Ogholikhan, S, Aigner, R, Winkler, J, Farrer, MJ, Gage, FH
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059106/
https://ncbi.nlm.nih.gov/pubmed/21168496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.12.008
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