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Activation of the stress proteome as a mechanism for small molecule therapeutics

Various small molecule pharmacologic agents with different known functions produce similar outcomes in diverse Mendelian and complex disorders, suggesting that they may induce common cellular effects. These molecules include histone deacetylase inhibitors, 4-phenylbutyrate (4PBA) and trichostatin A,...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Brose, Rebecca Deering, Shin, Gloria, McGuinness, Martina C., Schneidereith, Tonya, Purvis, Shirley, Dong, Gao X., Keefer, Jeffrey, Spencer, Forrest, Smith, Kirby D.
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441123/
https://ncbi.nlm.nih.gov/pubmed/22752410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds247
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