Therapeutic targeting of immune checkpoints with small molecule inhibitors

Immune checkpoints are known to contribute to tumor progression by enhancing cancer’s ability to evade the immune system and metastasize. Immunotherapies, including monoclonal antibodies, have been developed to target specific immunosuppressive molecules on the membranes of cancer cells and have pro...

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Foilsithe in:Am J Transl Res
Main Authors: Smith, Wade M, Purvis, Ian J, Bomstad, Colin N, Labak, Collin M, Velpula, Kiran K, Tsung, Andrew J, Regan, Jenna N, Venkataraman, Sujatha, Vibhakar, Rajeev, Asuthkar, Swapna
Formáid: Artigo
Teanga:Inglês
Foilsithe: e-Century Publishing Corporation 2019
Ábhair:
Review Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413273/
https://ncbi.nlm.nih.gov/pubmed/30899360
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