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Sculpting the proteome with small molecules
The ubiquitin-proteasome system (UPS) pervades the biology of eukaryotes. Because it depends on the activity of hundreds of different enzymes and protein-protein interactions, the UPS provides many opportunities for selective modulation of the pathway with small molecules. Here we discuss the princi...
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| Publicado en: | Nat Chem Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group US
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4639395/ https://ncbi.nlm.nih.gov/pubmed/25325686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1671 |
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