Identification of Novel Human Dipeptidyl Peptidase-IV Inhibitors of Natural Origin (Part I): Virtual Screening and Activity Assays

BACKGROUND: There has been great interest in determining whether natural products show biological activity toward protein targets of pharmacological relevance. One target of particular interest is DPP-IV whose most important substrates are incretins that, among other beneficial effects, stimulates i...

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Hlavní autoři: Guasch, Laura, Ojeda, Maria José, González-Abuín, Noemí, Sala, Esther, Cereto-Massagué, Adrià, Mulero, Miquel, Valls, Cristina, Pinent, Montserrat, Ardévol, Anna, Garcia-Vallvé, Santiago, Pujadas, Gerard
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440348/
https://ncbi.nlm.nih.gov/pubmed/22984596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044971
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