β3 Integrin in Cardiac Fibroblast Is Critical for Extracellular Matrix Accumulation during Pressure Overload Hypertrophy in Mouse

The adhesion receptor β3 integrin regulates diverse cellular functions in various tissues. As β3 integrin has been implicated in extracellular matrix (ECM) remodeling, we sought to explore the role of β3 integrin in cardiac fibrosis by using wild type (WT) and β3 integrin null (β3−/−) mice for in vi...

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Autors principals: Balasubramanian, Sundaravadivel, Quinones, Lakeya, Kasiganesan, Harinath, Zhang, Yuhua, Pleasant, Dorea L., Sundararaj, Kamala P., Zile, Michael R., Bradshaw, Amy D., Kuppuswamy, Dhandapani
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440340/
https://ncbi.nlm.nih.gov/pubmed/22984613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045076
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