Gene-Expression-Guided Selection of Candidate Loci and Molecular Phenotype Analyses Enhance Genetic Discovery in Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a highly heterogeneous autoimmune disorder characterized by differences in autoantibody profiles, serum cytokines, and clinical manifestations. We have previously conducted a case-case genome-wide association study (GWAS) of SLE patients to detect associations w...

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Hlavní autoři: Koldobskaya, Yelena, Ko, Kichul, Kumar, Akaash A., Agik, Sandra, Arrington, Jasmine, Kariuki, Silvia N., Franek, Beverly S., Kumabe, Marissa, Utset, Tammy O., Jolly, Meenakshi, Skol, Andrew D., Niewold, Timothy B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439981/
https://ncbi.nlm.nih.gov/pubmed/22988468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/682018
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