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Single-molecule microscopy reveals new insights into nucleotide selection by DNA polymerase I
The mechanism by which DNA polymerases achieve their extraordinary accuracy has been intensely studied because of the linkage between this process and mutagenesis and carcinogenesis. Here, we have used single-molecule fluorescence microscopy to study the process of nucleotide selection and exonuclea...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3439913/ https://ncbi.nlm.nih.gov/pubmed/22669904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks523 |
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