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Highly efficient generation of heritable zebrafish gene mutations using homo- and heterodimeric TALENs

Transcription activator-like effector nucleases (TALENs) are powerful new research tools that enable targeted gene disruption in a wide variety of model organisms. Recent work has shown that TALENs can induce mutations in endogenous zebrafish genes, but to date only four genes have been altered, and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cade, Lindsay, Reyon, Deepak, Hwang, Woong Y., Tsai, Shengdar Q., Patel, Samir, Khayter, Cyd, Joung, J. Keith, Sander, Jeffry D., Peterson, Randall T., Yeh, Jing-Ruey Joanna
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439908/
https://ncbi.nlm.nih.gov/pubmed/22684503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks518
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