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Heterochromatin protein 1 gamma and IκB kinase alpha interdependence during tumour necrosis factor gene transcription elongation in activated macrophages

IκB kinase α (IKKα) is part of the cytoplasmic IKK complex regulating nuclear factor-{kappa}B (NF-κB) release and translocation into the nucleus in response to pro-inflammatory signals. IKKα can also be recruited directly to the promoter of NF-κB-dependent genes by NF-κB where it phosphorylates hist...

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Autors principals: Thorne, James L., Ouboussad, Lylia, Lefevre, Pascal F.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439902/
https://ncbi.nlm.nih.gov/pubmed/22649058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks509
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