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A NF-κB-Dependent Dual Promoter-Enhancer Initiates the Lipopolysaccharide-Mediated Transcriptional Activation of the Chicken Lysozyme in Macrophages

The transcriptional activation of the chicken lysozyme gene (cLys) by lipopolysaccharide (LPS) in macrophages is dependent on transcription of a LPS-Inducible Non-Coding RNA (LINoCR) triggering eviction of the CCCTC-binding factor (CTCF) from a negative regulatory element upstream of the lysozyme tr...

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Detalhes bibliográficos
Main Authors: Witham, James, Ouboussad, Lylia, Lefevre, Pascal F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606415/
https://ncbi.nlm.nih.gov/pubmed/23533622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059389
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