The LPS-Induced Transcriptional Upregulation of the Chicken Lysozyme Locus Involves CTCF Eviction and Noncoding RNA Transcription

Transcription of the lysozyme gene is rapidly induced by proinflammatory stimuli such as treatment with bacterial lipopolysaccharide (LPS). Here we show that this induction involves both the relief of repression mediated by the enhancer-blocking protein CTCF that binds to a negative regulatory eleme...

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Bibliographic Details
Main Authors: Lefevre, Pascal, Witham, James, Lacroix, Claire E., Cockerill, Peter N., Bonifer, Constanze
Format: Artigo
Language:Inglês
Published: Cell Press 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581490/
https://ncbi.nlm.nih.gov/pubmed/18851839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.07.023
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