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Automated volumetric growth plate measurement using magnetic resonance imaging for monitoring skeletal toxicity in children treated on investigational drug trials
PURPOSE: Targeted anti-cancer agents have reported side effects on the skeletal system such as thickening of the epiphyseal growth plate in pre-clinical models of juvenile but not mature animals. Careful evaluation of skeletal toxicity in the clinical development of targeted therapies for children i...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3439140/ https://ncbi.nlm.nih.gov/pubmed/21807634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2259 |
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