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Preclincial Testing of Sorafenib and RAD001 in the Nf (fl/fl);DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging

BACKGROUND: Neurofibromatosis type 1 (NF1) is an inherited disease predisposing affected patients to variable numbers of benign neurofibromas. To date there are no effective chemotherapeutic drugs available for this slow growing tumor. Molecularly targeted agents that aim to slow neurofibroma growth...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wu, Jianqiang, Dombi, Eva, Jousma, Edwin, Dunn, R. Scott, Lindquist, Diana, Schnell, Beverly M., Kim, Mi-Ok, Kim, AeRang, Widemann, Brigitte C., Cripe, Timothy P., Ratner, Nancy
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128176/
https://ncbi.nlm.nih.gov/pubmed/21319287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.23015
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