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Preclincial Testing of Sorafenib and RAD001 in the Nf (fl/fl);DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging
BACKGROUND: Neurofibromatosis type 1 (NF1) is an inherited disease predisposing affected patients to variable numbers of benign neurofibromas. To date there are no effective chemotherapeutic drugs available for this slow growing tumor. Molecularly targeted agents that aim to slow neurofibroma growth...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3128176/ https://ncbi.nlm.nih.gov/pubmed/21319287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.23015 |
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