MicroRNA-155 contributes to plexiform neurofibroma growth downstream of MEK

MicroRNAs (miRs) are small non-coding RNAs that can have large impacts on oncogenic pathways. Possible functions of dysregulated miRs have not been studied in neurofibromatosis type 1 (NF1) plexiform neurofibromas (PNFs). In PNFs, Schwann cells (SCs) have biallelic NF1 mutations necessary for tumori...

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Publicado en:Oncogene
Main Authors: Na, Youjin, Hall, Ashley, Choi, Kwangmin, Hu, Liang, Rose, Jonathan, Coover, Robert A., Miller, Adam, Hennigan, Robert F., Dombi, Eva, Kim, Mi-Ok, Subramanian, Subbaya, Ratner, Nancy, Wu, Jianqiang
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7867646/
https://ncbi.nlm.nih.gov/pubmed/33293695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01581-9
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