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The in Vivo Role of Androgen Receptor SUMOylation as Revealed by Androgen Insensitivity Syndrome and Prostate Cancer Mutations Targeting the Proline/Glycine Residues of Synergy Control Motifs

The androgen receptor (AR) mediates the effects of male sexual hormones on development and physiology. Alterations in AR function are central to reproductive disorders, prostate cancer, and Kennedy disease. AR activity is influenced by post-translational modifications, but their role in AR-based dis...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mukherjee, Sarmistha, Cruz-Rodríguez, Osvaldo, Bolton, Eric, Iñiguez-Lluhí, Jorge A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438951/
https://ncbi.nlm.nih.gov/pubmed/22829593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.395210
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