Design and Characterization of Modular Scaffolds for Tubulin Assembly

In cells, microtubule dynamics is regulated by stabilizing and destabilizing factors. Whereas proteins in both categories have been identified, their mechanism of action is rarely understood at the molecular level. This is due in part to the difficulties faced in structural approaches to obtain atom...

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Autors principals: Mignot, Ingrid, Pecqueur, Ludovic, Dorléans, Audrey, Karuppasamy, Manikandan, Ravelli, Raimond B. G., Dreier, Birgit, Plückthun, Andreas, Knossow, Marcel, Gigant, Benoît
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Protein Structure and Folding
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438940/
https://ncbi.nlm.nih.gov/pubmed/22791712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.383869
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