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Structural insight into the inhibition of tubulin by vinca domain peptide ligands
The tubulin vinca domain is the target of widely different microtubule inhibitors that interfere with the binding of vinblastine. Although all these ligands inhibit the hydrolysis of GTP, they affect nucleotide exchange to variable extents. The structures of two vinca domain antimitotic peptides—pho...
में बचाया:
| मुख्य लेखकों: | , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Publishing Group
2008
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581847/ https://ncbi.nlm.nih.gov/pubmed/18787557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.171 |
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