Laddar...

Structural insight into the inhibition of tubulin by vinca domain peptide ligands

The tubulin vinca domain is the target of widely different microtubule inhibitors that interfere with the binding of vinblastine. Although all these ligands inhibit the hydrolysis of GTP, they affect nucleotide exchange to variable extents. The structures of two vinca domain antimitotic peptides—pho...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Cormier, Anthony, Marchand, Matthieu, Ravelli, Raimond B G, Knossow, Marcel, Gigant, Benoît
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581847/
https://ncbi.nlm.nih.gov/pubmed/18787557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.171
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!