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Native State Conformational Heterogeneity of HP35 Revealed by Time-Resolved FRET

The villin headpiece subdomain (HP35) has become one of the most widely used model systems in protein folding studies, due to its small size and ultrafast folding kinetics. Here, we use HP35 as a testbed to show that the florescence decay kinetics of an unnatural amino acids p-cyanophenylalanine (Ph...

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Detalhes bibliográficos
Main Authors: Serrano, Arnaldo L., Bilsel, Osman, Gai, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438901/
https://ncbi.nlm.nih.gov/pubmed/22891809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp211296e
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