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Native State Conformational Heterogeneity of HP35 Revealed by Time-Resolved FRET
The villin headpiece subdomain (HP35) has become one of the most widely used model systems in protein folding studies, due to its small size and ultrafast folding kinetics. Here, we use HP35 as a testbed to show that the florescence decay kinetics of an unnatural amino acids p-cyanophenylalanine (Ph...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3438901/ https://ncbi.nlm.nih.gov/pubmed/22891809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp211296e |
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