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Conformational Heterogeneity of a Leucine Enkephalin Analog in Aqueous Solution and SDS Micelles: Comparison of Time-Resolved FRET and Molecular Dynamics Simulations

We have undertaken time-resolved Förster resonance energy transfer (FRET) and molecular dynamics simulations to analyze conformations and conformational heterogeneity of an analog of leucine enkephalin in solution and in the presence of SDS micelles. Enkephalins are opioid pentapeptides that interac...

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Autors principals: Unruh, Jay R., Kuczera, Krzysztof, Johnson, Carey K.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780025/
https://ncbi.nlm.nih.gov/pubmed/19780516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp903302k
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