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Conformational Heterogeneity of a Leucine Enkephalin Analog in Aqueous Solution and SDS Micelles: Comparison of Time-Resolved FRET and Molecular Dynamics Simulations

We have undertaken time-resolved Förster resonance energy transfer (FRET) and molecular dynamics simulations to analyze conformations and conformational heterogeneity of an analog of leucine enkephalin in solution and in the presence of SDS micelles. Enkephalins are opioid pentapeptides that interac...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Unruh, Jay R., Kuczera, Krzysztof, Johnson, Carey K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780025/
https://ncbi.nlm.nih.gov/pubmed/19780516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp903302k
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