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Time-resolved FRET between GPCR ligands reveals oligomers in native tissues
G protein–coupled receptor (GPCR) oligomers have been proposed to play critical roles in cell signaling, but confirmation of their existence in a native context remains elusive, as no direct interactions between receptors have been reported. To demonstrate their presence in native tissues, we develo...
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3506176/ https://ncbi.nlm.nih.gov/pubmed/20622858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.396 |
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