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HIPPOCAMPAL ANGIOGENESIS AND PROGENITOR CELL PROLIFERATION ARE INCREASED WITH ANTIDEPRESSANT USE IN MAJOR DEPRESSION

BACKGROUND: Adult neurogenesis is coupled to angiogenesis in neurogenic niches in the dentate gyrus (DG) and increased by antidepressants in rodents. We hypothesized that, in major depressive disorder (MDD), antidepressants increase neural progenitor cells (NPCs) and capillaries in the human DG. MET...

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Bibliographische Detailangaben
Hauptverfasser:	Boldrini, Maura, Hen, René, Underwood, Mark D., Rosoklija, Gorazd B., Dwork, Andrew J., Mann, J. John, Arango, Victoria
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	2012
Schlagworte:	Article
Online Zugang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3438317/ https://ncbi.nlm.nih.gov/pubmed/22652019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2012.04.024
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HIPPOCAMPAL ANGIOGENESIS AND PROGENITOR CELL PROLIFERATION ARE INCREASED WITH ANTIDEPRESSANT USE IN MAJOR DEPRESSION

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