Resilience Is Associated With Larger Dentate Gyrus, While Suicide Decedents With Major Depressive Disorder Have Fewer Granule Neurons

BACKGROUND: Early life adversity (ELA) increases major depressive disorder (MDD) and suicide risk and potentially affects dentate gyrus (DG) plasticity. We reported smaller DG and fewer granular neurons (GNs) in MDD. ELA effects on DG plasticity in suicide decedents with MDD (MDDSui) and resilient s...

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Dettagli Bibliografici
Pubblicato in:Biol Psychiatry
Autori principali: Boldrini, Maura, Galfalvy, Hanga, Dwork, Andrew J., Rosoklija, Gorazd B., Trencevska-Ivanovska, Iskra, Pavlovski, Goran, Hen, René, Arango, Victoria, Mann, J. John
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830307/
https://ncbi.nlm.nih.gov/pubmed/30819514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2018.12.022
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