Resilience Is Associated With Larger Dentate Gyrus, While Suicide Decedents With Major Depressive Disorder Have Fewer Granule Neurons

BACKGROUND: Early life adversity (ELA) increases major depressive disorder (MDD) and suicide risk and potentially affects dentate gyrus (DG) plasticity. We reported smaller DG and fewer granular neurons (GNs) in MDD. ELA effects on DG plasticity in suicide decedents with MDD (MDDSui) and resilient s...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Boldrini, Maura, Galfalvy, Hanga, Dwork, Andrew J., Rosoklija, Gorazd B., Trencevska-Ivanovska, Iskra, Pavlovski, Goran, Hen, René, Arango, Victoria, Mann, J. John
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830307/
https://ncbi.nlm.nih.gov/pubmed/30819514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2018.12.022
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