Hippocampal Granule Neuron Number and Dentate Gyrus Volume in Antidepressant-Treated and Untreated Major Depression

Smaller hippocampal volume is reported in major depressive disorder (MDD). We hypothesize that it may be related to fewer granule neurons (GN) in the dentate gyrus (DG), a defect possibly reversible with antidepressants. We studied age-, sex-, and postmortem interval-matched groups: no major psychop...

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Detalhes bibliográficos
Main Authors: Boldrini, Maura, Santiago, Adrienne N, Hen, René, Dwork, Andrew J, Rosoklija, Gorazd B, Tamir, Hadassah, Arango, Victoria, John Mann, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629406/
https://ncbi.nlm.nih.gov/pubmed/23303074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.5
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