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Identification and Characterization of a Broadly Cross-Reactive HIV-1 Human Monoclonal Antibody That Binds to Both gp120 and gp41
Identification of broadly cross-reactive HIV-1-neutralizing antibodies (bnAbs) may assist vaccine immunogen design. Here we report a novel human monoclonal antibody (mAb), designated m43, which co-targets the gp120 and gp41 subunits of the HIV-1 envelope glycoprotein (Env). M43 bound to recombinant...
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主要な著者: | , , , , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Public Library of Science
2012
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3438192/ https://ncbi.nlm.nih.gov/pubmed/22970187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044241 |
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