Nucleic acid-containing amyloid fibrils potently induce type I interferon and stimulate systemic autoimmunity

The immunopathophysiologic development of systemic autoimmunity involves numerous factors through complex mechanisms that are not fully understood. In systemic lupus erythematosus, type I IFN (IFN-I) produced by plasmacytoid dendritic cells (pDCs) critically promotes the autoimmunity through its ple...

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Detaylı Bibliyografya
Asıl Yazarlar: Di Domizio, Jeremy, Dorta-Estremera, Stephanie, Gagea, Mihai, Ganguly, Dipyaman, Meller, Stephan, Li, Ping, Zhao, Bihong, Tan, Filemon K., Bi, Liqi, Gilliet, Michel, Cao, Wei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2012
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437876/
https://ncbi.nlm.nih.gov/pubmed/22904191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206923109
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