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Tyrosine Phosphatase Inhibition Induces an ASC-dependent Pyroptosis

Pyroptosis is a type of cell death in which danger associated molecular patterns (DAMPs) and pathogen associated molecular patterns (PAMPs) induce mononuclear phagocytes to activate caspase-1 and release mature IL-1β. Because the tyrosine kinase inhibitor AG126 can prevent DAMP/PAMP induced activati...

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Autors principals: Ghonime, Mohammed G., Shamaa, Obada R., Eldomany, Ramadan A., Gavrilin, Mikhail A., Wewers, Mark D.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437604/
https://ncbi.nlm.nih.gov/pubmed/22842458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.07.102
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