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Tyrosine Phosphatase Inhibition Induces an ASC-dependent Pyroptosis
Pyroptosis is a type of cell death in which danger associated molecular patterns (DAMPs) and pathogen associated molecular patterns (PAMPs) induce mononuclear phagocytes to activate caspase-1 and release mature IL-1β. Because the tyrosine kinase inhibitor AG126 can prevent DAMP/PAMP induced activati...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3437604/ https://ncbi.nlm.nih.gov/pubmed/22842458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.07.102 |
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