ロード中...

Mesalazine Reduces Mutations in Transforming Growth Factor β Receptor II and Activin Type II Receptor by Improvement of Replication Fidelity in Mononucleotide Repeats

PURPOSE: Mesalazine (5-aminosalicylic acid, 5-ASA) has chemopreventive properties in colitis-associated cancer. In vitro, it improves replication fidelity at (CA)13 microsatellites independent of mismatch repair proficiency. Therefore, 5-ASA might be advantageous in patients with hereditary nonpolyp...

詳細記述

保存先:
書誌詳細
主要な著者: Campregher, Christoph, Honeder, Clemens, Chung, Heekyung, Carethers, John M., Gasche, Christoph
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437339/
https://ncbi.nlm.nih.gov/pubmed/20197483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-2854
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!