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The nucleotide composition of microsatellites impacts both replication fidelity and mismatch repair in human colorectal cells
Microsatellite instability is a key mechanism of colon carcinogenesis. We have previously studied mutations within a (CA)13 microsatellite using an enhanced green fluorescent protein (EGFP)-based reporter assay that allows the distinction of replication errors and mismatch repair (MMR) activity. Her...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2883347/ https://ncbi.nlm.nih.gov/pubmed/20421367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq175 |
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