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The nucleotide composition of microsatellites impacts both replication fidelity and mismatch repair in human colorectal cells
Microsatellite instability is a key mechanism of colon carcinogenesis. We have previously studied mutations within a (CA)13 microsatellite using an enhanced green fluorescent protein (EGFP)-based reporter assay that allows the distinction of replication errors and mismatch repair (MMR) activity. Her...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2883347/ https://ncbi.nlm.nih.gov/pubmed/20421367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq175 |
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