Nalaganje...
DOCK8 mutations cripple B cell immune synapse, germinal centers and long-lived antibody production
To illuminate genes and mechanisms for humoral immunity we performed a mouse genetic screen for mutations that do not affect the first wave of antibody to immunization but disrupt response maturation and persistence. The first two mutants identified were loss-of-function mutations in DOCK8. DOCK8 mu...
Shranjeno v:
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3437189/ https://ncbi.nlm.nih.gov/pubmed/19898472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1820 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|