Metabolism of Vertebrate Amino Sugars with N-Glycolyl Groups: RESISTANCE OF α2–8-LINKED N-GLYCOLYLNEURAMINIC ACID TO ENZYMATIC CLEAVAGE

The sialic acid (Sia) N-acetylneuraminic acid (Neu5Ac) and its hydroxylated derivative N-glycolylneuraminic acid (Neu5Gc) differ by one oxygen atom. CMP-Neu5Gc is synthesized from CMP-Neu5Ac, with Neu5Gc representing a highly variable fraction of total Sias in various tissues and among different spe...

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Detalhes bibliográficos
Main Authors: Davies, Leela R. L., Pearce, Oliver M. T., Tessier, Matthew B., Assar, Siavash, Smutova, Victoria, Pajunen, Maria, Sumida, Mizuki, Sato, Chihiro, Kitajima, Ken, Finne, Jukka, Gagneux, Pascal, Pshezhetsky, Alexey, Woods, Robert, Varki, Ajit
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436535/
https://ncbi.nlm.nih.gov/pubmed/22692207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.365056
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