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Why Is N-Glycolylneuraminic Acid Rare in the Vertebrate Brain?

The sialic acids N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc) differ by a single oxygen atom and are widely found at the terminal position of glycans on vertebrate cell surfaces. In animals capable of synthesizing Neu5Gc, most tissues and cell types express both sialic aci...

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Detalhes bibliográficos
Main Authors: Davies, Leela R.L., Varki, Ajit
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026345/
https://ncbi.nlm.nih.gov/pubmed/23471785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/128_2013_419
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