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The Werner Syndrome Protein Promotes CAG/CTG Repeat Stability by Resolving Large (CAG)(n)/(CTG)(n) Hairpins
Expansion of CAG/CTG repeats causes certain neurological and neurodegenerative disorders, and the formation and subsequent persistence of stable DNA hairpins within these repeats are believed to contribute to CAG/CTG repeat instability. Human cells possess a DNA hairpin repair (HPR) pathway, which r...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3436269/ https://ncbi.nlm.nih.gov/pubmed/22787159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.389791 |
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