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Incision-Dependent and Error-Free Repair of (CAG)(n)/(CTG)(n) Hairpins in Human Cell Extracts
Expansion of CAG/CTG trinucleotide repeats is associated with certain familial neurological disorders, including Huntington's disease. Increasing evidence suggests that formation of a stable DNA hairpin within CAG/CTG repeats during DNA metabolism contributes to their expansion. However, the mo...
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| Опубликовано в: : | Nat Struct Mol Biol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5039229/ https://ncbi.nlm.nih.gov/pubmed/19597480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1638 |
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