Protein Arginine Methyltransferase 7 Regulates Cellular Response to DNA Damage by Methylating Promoter Histones H2A and H4 of the Polymerase δ Catalytic Subunit Gene, POLD1

Covalent modification of histones by protein arginine methyltransferases (PRMTs) impacts genome organization and gene expression. In this report, we show that PRMT7 interacts with the BRG1-based hSWI/SNF chromatin remodeling complex and specifically methylates histone H2A Arg-3 (H2AR3) and histone H...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Karkhanis, Vrajesh, Wang, Li, Tae, Sookil, Hu, Yu-Jie, Imbalzano, Anthony N., Sif, Saïd
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Gene Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436169/
https://ncbi.nlm.nih.gov/pubmed/22761421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.378281
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares