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Protein Arginine Methyltransferase 7 Regulates Cellular Response to DNA Damage by Methylating Promoter Histones H2A and H4 of the Polymerase δ Catalytic Subunit Gene, POLD1

Covalent modification of histones by protein arginine methyltransferases (PRMTs) impacts genome organization and gene expression. In this report, we show that PRMT7 interacts with the BRG1-based hSWI/SNF chromatin remodeling complex and specifically methylates histone H2A Arg-3 (H2AR3) and histone H...

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Autors principals: Karkhanis, Vrajesh, Wang, Li, Tae, Sookil, Hu, Yu-Jie, Imbalzano, Anthony N., Sif, Saïd
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436169/
https://ncbi.nlm.nih.gov/pubmed/22761421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.378281
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