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The NAD(+)-dependent protein deacetylase activity of SIRT1 is regulated by its oligomeric status
SIRT1, a NAD(+)-dependent protein deacetylase, is an important regulator in cellular stress response and energy metabolism. While the list of SIRT1 substrates is growing, how the activity of SIRT1 is regulated remains unclear. We have previously reported that SIRT1 is activated by phosphorylation at...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3435561/ https://ncbi.nlm.nih.gov/pubmed/22962634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00640 |
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