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Mechanism of Sirt1 NAD(+)-dependent Protein Deacetylase Inhibition by Cysteine S-Nitrosation

The sirtuin family of proteins catalyze the NAD(+)-dependent deacylation of acyl-lysine residues. Humans encode seven sirtuins (Sirt1–7), and recent studies have suggested that post-translational modification of Sirt1 by cysteine S-nitrosation correlates with increased acetylation of Sirt1 deacetyla...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Kalous, Kelsey S., Wynia-Smith, Sarah L., Olp, Michael D., Smith, Brian C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207242/
https://ncbi.nlm.nih.gov/pubmed/27756843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.754655
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