Inferring transcriptional and microRNA-mediated regulatory programs in glioblastoma

Large-scale cancer genomics projects are profiling hundreds of tumors at multiple molecular layers, including copy number, mRNA and miRNA expression, but the mechanistic relationships between these layers are often excluded from computational models. We developed a supervised learning framework for...

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Detalhes bibliográficos
Main Authors: Setty, Manu, Helmy, Karim, Khan, Aly A, Silber, Joachim, Arvey, Aaron, Neezen, Frank, Agius, Phaedra, Huse, Jason T, Holland, Eric C, Leslie, Christina S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435504/
https://ncbi.nlm.nih.gov/pubmed/22929615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2012.37
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