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SeqGL Identifies Context-Dependent Binding Signals in Genome-Wide Regulatory Element Maps
Genome-wide maps of transcription factor (TF) occupancy and regions of open chromatin implicitly contain DNA sequence signals for multiple factors. We present SeqGL, a novel de novo motif discovery algorithm to identify multiple TF sequence signals from ChIP-, DNase-, and ATAC-seq profiles. SeqGL tr...
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| Publicado en: | PLoS Comput Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4446265/ https://ncbi.nlm.nih.gov/pubmed/26016777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004271 |
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