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Clustered ChIP-Seq-defined transcription factor binding sites and histone modifications map distinct classes of regulatory elements

BACKGROUND: Transcription factor binding to DNA requires both an appropriate binding element and suitably open chromatin, which together help to define regulatory elements within the genome. Current methods of identifying regulatory elements, such as promoters or enhancers, typically rely on sequenc...

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Autores principales: Rye, Morten, Sætrom, Pål, Håndstad, Tony, Drabløs, Finn
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3239327/
https://ncbi.nlm.nih.gov/pubmed/22115494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-9-80
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