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A ChIP-Seq Benchmark Shows That Sequence Conservation Mainly Improves Detection of Strong Transcription Factor Binding Sites

BACKGROUND: Transcription factors are important controllers of gene expression and mapping transcription factor binding sites (TFBS) is key to inferring transcription factor regulatory networks. Several methods for predicting TFBS exist, but there are no standard genome-wide datasets on which to ass...

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Detalhes bibliográficos
Main Authors: Håndstad, Tony, Rye, Morten Beck, Drabløs, Finn, Sætrom, Pål
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077367/
https://ncbi.nlm.nih.gov/pubmed/21533218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018430
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