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A context-based approach to identify the most likely mapping for RNA-seq experiments
BACKGROUND: Sequencing of mRNA (RNA-seq) by next generation sequencing technologies is widely used for analyzing the transcriptomic state of a cell. Here, one of the main challenges is the mapping of a sequenced read to its transcriptomic origin. As a simple alignment to the genome will fail to iden...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3358662/ https://ncbi.nlm.nih.gov/pubmed/22537048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-S6-S9 |
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