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A context-based approach to identify the most likely mapping for RNA-seq experiments

BACKGROUND: Sequencing of mRNA (RNA-seq) by next generation sequencing technologies is widely used for analyzing the transcriptomic state of a cell. Here, one of the main challenges is the mapping of a sequenced read to its transcriptomic origin. As a simple alignment to the genome will fail to iden...

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Autores principales: Bonfert, Thomas, Csaba, Gergely, Zimmer, Ralf, Friedel, Caroline C
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358662/
https://ncbi.nlm.nih.gov/pubmed/22537048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-S6-S9
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