Inferring transcriptional and microRNA-mediated regulatory programs in glioblastoma

Large-scale cancer genomics projects are profiling hundreds of tumors at multiple molecular layers, including copy number, mRNA and miRNA expression, but the mechanistic relationships between these layers are often excluded from computational models. We developed a supervised learning framework for...

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Hlavní autoři: Setty, Manu, Helmy, Karim, Khan, Aly A, Silber, Joachim, Arvey, Aaron, Neezen, Frank, Agius, Phaedra, Huse, Jason T, Holland, Eric C, Leslie, Christina S
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435504/
https://ncbi.nlm.nih.gov/pubmed/22929615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2012.37
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