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Valosin-Containing Protein (VCP/p97) Is an Activator of Wild-Type Ataxin-3
Alterations in the ubiquitin-proteasome system (UPS) have been reported in several neurodegenerative disorders characterized by protein misfolding and aggregation, including the polylgutamine diseases. Machado-Joseph disease (MJD) or Spinocerebellar Ataxia type 3 is caused by a polyglutamine-encodin...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3435318/ https://ncbi.nlm.nih.gov/pubmed/22970133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043563 |
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